There are many types of lesions (abnormal region of tissue) and tumors (abnormal growth of tissue) that can occur on the hand. Most are benign, but some can be cancerous. It’s important to individually evaluate each lesion or tumor. In some cases, a biopsy may be necessary to determine what the lesion or tumor is and whether it is cancerous. After the pathology (lab) report has been reviewed, your doctor can determine how best to treat or remove the lesion or tumor.